MCI alleviates inflammation by macrophage reprogramming via targeting ROS scavenging and COX-2 downregulation. MCI inhibits COX-2 with an IC50 value of 1.23 µM. MCI has significant anti-inflammatory effects in collagen-induced arthritis (CIA) models. MCI can be used in research for rheumatoid arthritis (RA)[1].
Molecular Weight:
934.39
Formula:
C45H52ClN7O13
Target:
COX,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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