Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC50s of 0.74 µM, 1.05 µM, 3.5 µM, and 4.9 µM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites[1].
Molecular Weight:
465.92
Formula:
C26H22ClF2N3O
Target:
Parasite
Application Notes:
MCE Product type: Reference compound1
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