SB-1295 is an orally active CDK9/T1 inhibitor (IC50=0.17 µM). SB-1295 shows antiproliferative activity in HCT 116 and MIA PaCa-2 cells. SB-1295 also induces MIA PaCa-2 cell death by inducing intracellular ROS production, reducing mitochondrial membrane potential and inducing apoptosis. SB-1295 has the potential to study cancer[1].
Molecular Weight:
443.88
Formula:
C23H22ClNO6
Target:
Apoptosis,CDK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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