PD-L1-IN-3 (Compound 4a) is a compound that targets PD-1/PD-L1, the IC50 value and EC50 value is 4.97nM and 2.70 µM for inhibit PD-L1 and Jurkat T cells, respectively. PD-L1-IN-3 can bind PD-L1 dimer to prevent PD-1 binding to PD-L1, therefore blocking PD-1 signaling. PD-L1-IN-3 can be used for lung cancer and melanoma diseases research[1].
Molecular Weight:
374.86
Purity:
99.69
CAS Number:
[2953044-29-4]
Formula:
C19H16ClFN2OS
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound1
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