SMA4 is a selective PKG1alpha activator with basal EC50 value of 29 µM. SMA4 facilitates phosphorylation of the known PKG1 substrate, vasodilator-stimulated phosphoprotein (VASP), and inhibits human pulmonary arterial smooth muscle cells (hPASMC) proliferation. SMA4 can be used for cardiovascular disease research[1].
Molecular Weight:
540.44
Purity:
98.52
Formula:
C28H27Cl2N3O4
Target:
PKG
Application Notes:
MCE Product type: Reference compound
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