COX-2/15-LOX-IN-4 (compound 5i) is a dual inhibitor of COX-2/15-LOX with IC50s of 0.075 µM and 1.97 µM, respectively. COX-2/15-LOX-IN-4 can inhibit LPS-induced cell production of promoting cytokines (IL-6, ROS) with specific anti-inflammatory activity[1].
Molecular Weight:
405.49
Formula:
C23H20FN3OS
Target:
COX,Lipoxygenase
Application Notes:
MCE Product type: Reference compound1
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