Antiproliferative agent-34, CAS [[2910858-34-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-155178
Supplier Catalog Number:
HY-155178
Alternative Catalog Number:
MCE-HY-155178-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Antiproliferative agent-34 (Compound A14) is a multi-target kinase inhibitor, with an IC50 of 177 nM and 1567 nM for EGFR L858R/T790M and EGFR WT. Antiproliferative agent-34 also inhibits JAK2, ROS1, FLT3, FLT4, PDGFRalpha with IC50 of 30.93, 106.90, 108.00, 226.60, 42.53 nM. Antiproliferative agent-34 inhibits H1975 and HCC827 cells proliferation with IC50 values below 40 nM under normoxic condition, and the anti-proliferation potency achieves 4-6-fold improvement (IC50 values [1].
Molecular Weight:
529.55
CAS Number:
[2910858-34-1]
Formula:
C27H27N7O5
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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