ZMF-23 is a PAK1/HDAC6 dual inhibitor. ZMF-23 inhibits PAK1 and HDAC6 regulated aerobic glycolysis and migration. ZMF-23 induces TNF-alpha-regulated necroptosis, and further enhances apoptosis. ZMF-23 inhibits the Warburg effect and cell migration. ZMF-23 can be used for research of triple-negative breast cancer (TNBC)[1].
Molecular Weight:
476.36
Formula:
C22H23Cl2N5O3
Target:
HDAC,PAK
Application Notes:
MCE Product type: Reference compound
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