XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 µM in AlphaLISA assay, and 4.59 µM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNgamma biomarkers in the graft versus host disease (GVHD) mice model[1].
Molecular Weight:
499.65
Purity:
99.77
Formula:
C30H37N5O2
Target:
Interleukin Related
Application Notes:
MCE Product type: Reference compound
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