TH9028 is an inhibitor of MTHFD2 (IC50 = 11 nM) with IC50 values against hMTHFD2, MTHFD2L, and MTHFD1 being 7.97 nM, 27 nM, and 0.5 nM, respectively. TH9028 also exhibits anti-cancer cell proliferation activity[1][2].
Molecular Weight:
458.39
CAS Number:
[2379556-15-5]
Formula:
C16H18N12O5
Target:
Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Application Notes:
MCE Product type: Reference compound
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