GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680 µM. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model [1].
Molecular Weight:
515.98
Purity:
99.88
Formula:
C30H26ClNO5
Target:
ERK,Orphan GPCR,Orphan Receptor
Application Notes:
MCE Product type: Reference compound
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