Me4Phen (compound 3) is an oxygen rhenium (V) complex that depletes mitochondrial membrane potential and upregulates intracellular reactive oxygen species (ROS), leading to endoplasmic reticulum stress-mediated necrosis of cancer cells. Me4Phen is highly lipophilic and effectively overcomes Cisplatin (HY-17394) resistance in a variety of cancer cells[1].
Molecular Weight:
534.02
Formula:
C18H20ClN2O3Re
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound1
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