PqsR-IN-3 (compound 16e) is a selective inhibitor of the pqs system (IC50=3.7 µM) and its associated virulence factor pyocyanin (IC50=2.7 µM). PqsR-IN-3 inhibits bacterial biofilm synthesis and is significantly cytotoxic against Pseudomonas aeruginosa. PqsR-IN-3 has synergistic effects with several antibiotics, such as Ciprofloxacin (HY-B0356) and Tobramycin (HY-B0441)[1].
Molecular Weight:
417.46
CAS Number:
[3033007-79-0]
Formula:
C23H23N5O3
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound1
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