Antileishmanial agent-19

Catalog Number: MCE-HY-155520
Article Name: Antileishmanial agent-19
Biozol Catalog Number: MCE-HY-155520
Supplier Catalog Number: HY-155520
Alternative Catalog Number: MCE-HY-155520-50MG,MCE-HY-155520-25MG,MCE-HY-155520-10MG,MCE-HY-155520-5MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Antileishmanial agent-19 (Compound F27) is an antileishmanial agent, with a IC50 of 3.39 µM for L. donovani promastigotes. Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase. Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes. Antileishmanial agent-19 reduces parasite burden in L.d-infected animals[1].
Molecular Weight: 386.40
Purity: 99.45
Formula: C22H18N4O3
Target: Parasite
Application Notes: MCE Product type: Reference compound1