SARS-CoV-2 Mpro-IN-9 (compound c7) is a nonpeptidic, noncovalent SARS-CoV-2 Mpro inhibitor (IC50=0.085 µM), with improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. SARS-CoV-2 Mpro-IN-9 inhibits viral replication (EC50=1.10 µM) in SARS-CoV-2-infected Vero E6 cells, while exhibits low cytotoxic effects (CC50>50 µM)[1].
Molecular Weight:
346.34
CAS Number:
[2754370-99-3]
Formula:
C20H14N2O4
Target:
SARS-CoV
Application Notes:
MCE Product type: Reference compound
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