FD1024 is PIM inhibitor (IC50s: 1.96, 38.9, 4.17 nM for PIM1, 2, 3). FD1024 can be used for research of acute myeloid leukemia. FD1024 has strong antiproliferative activity against the tested AML cell lines, with 0.16 µM, 0.12 µM, 1.05 µM, 1.39µM for EOL-1, MV-4-11, KG-1, MOLM-16 cells. FD1024 also has antitumor efficacy in mice[1].
Molecular Weight:
430.47
CAS Number:
[1422456-47-0]
Formula:
C21H20F2N4O2S
Target:
Pim
Application Notes:
MCE Product type: Reference compound
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