ZG36 is a human Caseinolytic protease P (ClpP) agonist. ZG36 non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, ultimately leading to mitochondrial dysfunction and leukemic cell death. ZG36 also inhibits the development of acute myeloid leukemia in a xenograft mouse model[1].
Molecular Weight:
607.54
CAS Number:
[2999673-34-4]
Formula:
C31H35BrN4O4
Target:
ClpP
Application Notes:
MCE Product type: Reference compound
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