Nrf2 activator-8 (compound 10e) is a Nrf2 activator (EC50=37.9 nM). Nrf2 activator-8 exhibits remarkable antioxidant and anti-inflammatory effects in BV-2 microglial cells. Nrf2 activator-8 can significantly restore spatial memory deficits in a mouse model of lipopolysaccharide (LPS)-induced neuroinflammation[1].
Molecular Weight:
310.76
Formula:
C13H11ClN2O3S
Target:
Keap1-Nrf2
Application Notes:
MCE Product type: Reference compound
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