SA-PA is an intracellular self-assembled PROTAC based on azide and alkyne. SA-PA is able to selectively degrade VEGFR-2, PDGFR-beta and EphB4 proteins in U87 cells. SA-PA can be converted to PROTAC in situ by click reaction with the help of endogenous copper in tumor tissues[1].
Molecular Weight:
873.19
Formula:
C40H32ClF3N10O8
Target:
Ephrin Receptor,PDGFR,PROTACs,VEGFR
Application Notes:
MCE Product type: Reference compound
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