PDE5-IN-10 (compound 4b) is a potent PDE5 inhibitor with an IC50 of 20 nM. PDE5-IN-10 improves in vitro microsomal stability (t1/2 = 44.6 min) as well as excellent efficacy in restoring long-term potentiation. PDE5-IN-10 can be used for Alzheimers disease (AD) research[1].
Molecular Weight:
360.41
Formula:
C21H20N4O2
Target:
Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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