hCA/VEGFR-2-IN-1 (compound 13a) is a potent dual Carbonic Anhydrase(CA) IX/XII with Ki values of 4.7 nM and 8.3 nM for hCA XII and hCA IX, respectively. hCA/VEGFR-2-IN-1 (compound 13a) is a potent VEGFR-2 inhibitor with IC50 values 26.3 nM. hCA/VEGFR-2-IN-1 has anticancer activity[1].
Molecular Weight:
452.46
Formula:
C21H17FN6O3S
Target:
Carbonic Anhydrase,VEGFR
Application Notes:
MCE Product type: Reference compound
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