Mtb-IN-4 (compound 17h) is a nontoxic isoxazole, with anti-Mycobacterium tuberculosis (Mtb) activity (IC50=0.70 µM). Mtb-IN-4 inhibits Mtb respiration and biofilm formation in macrophage, and enhances antibiotic isoniazid (INH) inhibition against INH-resistant Mtb mutant[1].
Molecular Weight:
430.48
CAS Number:
[2306039-13-2]
Formula:
C24H18N2O4S
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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