Sirt1/2-IN-3, CAS [[301313-42-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-155728
Supplier Catalog Number:
HY-155728
Alternative Catalog Number:
MCE-HY-155728-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Sirt1/2-IN-3 (compound PS9) is a dual inhibitor of SIRT1/2 with IC50s of 1.4 µM (SIRT1) and 2.0 µM (SIRT2), respsectivley. Sirt1/2-IN-3 completely blocks p53 deacetylation, and increase of p53 and alpha-tubulin acetylation. Sirt1/2-IN-3 induces apoptosis and shows anti-proliferation activity against human leukemia cell lines[1].
Molecular Weight:
363.82
CAS Number:
[301313-42-8]
Formula:
C17H14ClNO4S
Target:
Apoptosis,Sirtuin
Application Notes:
MCE Product type: Reference compound
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