JAK2-IN-9 (Compound A8) is a selective JAK2 inhibitor (IC50: 5 nM). JAK2-IN-9 inhibits the phosphorylation of JAK2, STAT3, and STAT5. JAK2-IN-9 has metabolic stabilities. JAK2-IN-9 induces apoptosis. JAK2-IN-9 can be used for research of myeloproliferative neoplasms (MPNs)[1].
Molecular Weight:
412.51
CAS Number:
[2568842-26-0]
Formula:
C20H24N6O2S
Target:
JAK
Application Notes:
MCE Product type: Reference compound
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