McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) (HY-15579) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4].
Molecular Weight:
925.16
Purity:
99.97
CAS Number:
[863971-19-1]
Formula:
C49H76N6O11
Target:
Apoptosis,Drug-Linker Conjugates for ADC
Application Notes:
MCE Product type: ADC Related
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