SPC-180002, CAS [[2170274-53-8]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-155784
Supplier Catalog Number:
HY-155784
Alternative Catalog Number:
MCE-HY-155784-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SPC-180002 is a SIRT1/3 dual inhibitor, with IC50 values of 1.13 and 5.41 µM, respectively. SPC-180002 disturbs redox homeostasis via ROS generation, which leads to an increase in both p21 protein stability and mitochondrial dysfunction. SPC-180002 strongly inhibits cell cycle progression and cancer cell growth. SPC-180002 activates the Nrf2 signaling pathway[1].
Molecular Weight:
317.38
CAS Number:
[2170274-53-8]
Formula:
C18H23NO4
Target:
Keap1-Nrf2,Reactive Oxygen Species (ROS),Sirtuin
Application Notes:
MCE Product type: Reference compound
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