SHR5428 is a potent, orally active, selective and noncovalent inhibitor of CDK7 with highly potent CDK7 enzymatic activity (IC50=2.3 nM). SHR5428 inhibits triple negative breast cancer cellular activity on MDA-MB-468 cell (IC50=6.6 nM)[1].
Molecular Weight:
477.42
CAS Number:
[3054791-71-5]
Formula:
C22H23F3N5O2P
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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