CAF-382 (compound B1) is an analog of SNS-032 and a CDKL5 and pan-CDK inhibitor with a weak GSK3alpha/beta affinity (>1.8 µM) and inhibitory activity. CAF-382 inhibits CDKL5 and blocks the phosphorylation of the CDKL5 E2 domain[1].
Molecular Weight:
366.50
Purity:
98.15
Formula:
C16H22N4O2S2
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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