DPP is a Platinum(IV) complex, bearing pterostilbene-derived axial ligand. DPP inhibit the JAK2-STAT3 pathway in breast cancer (BC) cells with antiproliferative activity, and activates caspase-3 and cleaved poly ADP-ribose polymerase to induces apoptosis. DPP promotes the maturation and antigen presentation of dendritic cells, and exhibits in vivo safety[1].
Molecular Weight:
926.70
CAS Number:
[2668267-47-6]
Formula:
C36H40Cl2N2O10Pt
Target:
Apoptosis,JAK,STAT
Application Notes:
MCE Product type: Reference compound
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