Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].
Molecular Weight:
587.67
Purity:
99.08
CAS Number:
[228266-41-9]
Formula:
C29H44F3N3O6
Target:
ADC Payload,Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: ADC Related
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