Taltobulin hydrochloride (HTI-286 hydrochloride), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin hydrochloride inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis[1].
Molecular Weight:
510.11
Purity:
99.67
Formula:
C27H44ClN3O4
Target:
ADC Payload,Apoptosis,Microtubule/Tubulin
Application Notes:
MCE Product type: ADC Related
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