CIAC001 is a Pyruvate Kinase PKM2 inhibitor with anti-neuroinflammatory activity. CIAC001 inhibits LPS-induced proinflammatory nitric oxide (NO) production and protects immunologically active BV-2 cells (IC50=2.5 µM). CIAC001 also has anti-neuroinflammation in mouse models and inhibits chronic morphine-induced addiction[1].
Molecular Weight:
339.43
Purity:
99.70
CAS Number:
[2649154-82-3]
Formula:
C20H25N3O2
Target:
Pyruvate Kinase
Application Notes:
MCE Product type: Reference compound
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