Lepadin H is a marine alkaloid and ferroptosis inducer. Lepadin H exhibits significant cytotoxicity, promotes p53 expression, increases ROS production and lipid peroxidation, decreases SLC7A11 and GPX4 levels, and upregulates ACSL4 expression. Lepadin H induces ferroptosis through the p53-SLC7A11-GPX4 pathway[1].
Molecular Weight:
419.64
CAS Number:
[412328-25-7]
Formula:
C26H45NO3
Target:
Ferroptosis
Application Notes:
MCE Product type: Natural Products
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