IV-255 is a selective small molecule inhibitor of the BRG1 bromodomain. IV-255 increases the extent of DNA damage induced by Temozolomide (HY-17364) and Bleomycin (HY-108345). IV-255 inhibits the invasiveness of GBM cells. IV-255 enhances Temozolomide-induced cell death and the apoptosis-inducing activity of Temozolomide[1].
Molecular Weight:
359.37
Purity:
98.41
Formula:
C19H19F2N3O2
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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