VEGFR/PARP-IN-1, CAS [[3010256-54-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-155965
Supplier Catalog Number:
HY-155965
Alternative Catalog Number:
MCE-HY-155965-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
VEGFR/PARP-IN-1 (Compound 14b) is a VEGFR/PARP dual inhibitor (IC50s: 191 nM and 60.9 nM respectively). VEGFR/PARP-IN-1 inhibits DNA damage repair, induces cell apoptosis, and arrests cell in the G2/M phase. VEGFR/PARP-IN-1 has good antiproliferative efficacy against BRCA wild-type breast cancer cells (IC50: 4.1 and 3.5 µM for MDA-MB-231 and MCF-7 cells). VEGFR/PARP-IN-1 is an antitumor and anti-metastasis agent[1].
Molecular Weight:
517.58
CAS Number:
[3010256-54-6]
Formula:
C29H27N9O
Target:
Apoptosis,PARP,VEGFR
Application Notes:
MCE Product type: Reference compound
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