PIK5-12d, CAS [[3036457-38-9]]

Product Overview

• Article Name: PIK5-12d, CAS [[3036457-38-9]]
• Biozol Catalog Number: MCE-HY-155994
• Supplier Catalog Number: HY-155994
• Alternative Catalog Number: MCE-HY-155994-10MG,MCE-HY-155994-10MMX1ML,MCE-HY-155994-1MG,MCE-HY-155994-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PIK5-12d is a PROTAC PIKfyve degrader (DC50 = 1.48 nM). PIK5-12d induces massive cytoplasmic vacuolization and blocks autophagic flux in multiple prostate cancer cells. PIK5-12d inhibits prostate cancer cell proliferation. PIK5-12d significantly suppresses tumor proliferation in mice bearing LTL-331R human prostate cancer PDX tumors. PIK5-12d can be used for the study of prostate cancer. (Pink: PIKfyve ligand (HY-175631), Blue: VHL Ligand (HY-125845), Black: Linker, PIKfyve ligand-linker conjugate (HY-175632))[1].

Product Properties

• Molecular Weight: 973.19
• Purity: 99.15
• CAS Number: [3036457-38-9]
• Formula: C52H64N10O7S
• Target: Autophagy,PIKfyve,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound