SIRT6-IN-3, CAS [[3023471-40-8]]

Product Overview

• Article Name: SIRT6-IN-3, CAS [[3023471-40-8]]
• Biozol Catalog Number: MCE-HY-156027
• Supplier Catalog Number: HY-156027
• Alternative Catalog Number: MCE-HY-156027-25MG,MCE-HY-156027-50MG,MCE-HY-156027-10MG,MCE-HY-156027-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SIRT6-IN-3 (compound 8a) is a selective inhibitor of SIRT6 (IC50=7.49 µM). SIRT6-IN-3 inhibits pancreatic ductal adenocarcinoma (PDAC) cells proliferation and induces apoptosis. SIRT6-IN-3 increases the sensitivity of cancer cells to gemcitabine (HY-17026) via blocking the DNA damage repair pathway. SIRT6-IN-3 is used in pancreatic cancer research[1].

Product Properties

• Molecular Weight: 673.73
• Purity: 98.19
• CAS Number: [3023471-40-8]
• Formula: C21H30Br3ClN6S
• Target: Akt,ERK,HDAC,mTOR,Ribosomal S6 Kinase (RSK),Sirtuin

Application Notes

• Application Notes: MCE Product type: Reference compound