Menin-MLL inhibitor 29 (Compound C1) is a Menin-MLL PPI inhibitor. Menin-MLL inhibitor 29 binds to Menin with a KD value of 138 nM, and inhibits the binding of Menin to MBM1 (Menin-binding motif 1) with an IC50 value of 46 nM. Menin-MLL inhibitor 29 inhibits HepG2 and Hep3B hepatoma cell proliferation (IC50s: 0.31 µM and 0.71 µM). Menin-MLL inhibitor 29 inhibits tumor growth[1].
Molecular Weight:
922.30
Formula:
C36H26Br2F6N4PRh
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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