CYP51/PD-L1-IN-3, CAS [[3032386-59-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-156151
Supplier Catalog Number:
HY-156151
Alternative Catalog Number:
MCE-HY-156151-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CYP51/PD-L1-IN-3 (compound L21) is a quinazoline compound with antifungal activity. CYP51/PD-L1-IN-3 is a dual inhibitor of CYP51 (IC50: 0.205 µM) and PD-L1 (IC50: 0.039 µM), which can induce early apoptosis of fungal cells in the cell cycle. CYP51/PD-L1-IN-3 also significantly reduced intracellular IL-2, NLRP3, and NF-kappaBp65 protein levels, induced mitochondrial damage and ROS accumulation, and ultimately led to fungal lysis and death[1].
Molecular Weight:
468.55
CAS Number:
[3032386-59-4]
Formula:
C27H28N6O2
Target:
Cytochrome P450,Fungal,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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