Beclin1-ATG14L interaction inhibitor 1 (com 19) is a selective Beclin1-ATG14L interaction inhibitor. This protein interaction mechanism specifically targets complex I of the lipid kinase VPS34 without affecting complex II. Because the integrity of VPS34 complex II depends on the Beclin 1-UVRAG interaction. Beclin1-ATG14L interaction inhibitor 1 can disrupt the formation of VPS34 complex I and inhibit autophagy, but does not affect complex II-related vesicle transport[1].
Molecular Weight:
468.53
Purity:
99.88
CAS Number:
[1243063-73-1]
Formula:
C23H24N4O5S
Target:
Autophagy
Application Notes:
MCE Product type: Reference compound
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