IHMT-EZH2-426, CAS [[3018914-66-1]] Preis auf Anfrage

Product Overview

• Article Name: IHMT-EZH2-426, CAS [[3018914-66-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-156292
• Supplier Catalog Number: HY-156292
• Alternative Catalog Number: MCE-HY-156292-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

IHMT-EZH2-426 (compound 38) is an effective covalent EZH2 degrader, with IC50 values of 1.3 nM, 1.2 nM, and 1.7-3.5 nM for EZH2 wild type, EZH2-A687V, and EZH2-Y641F/Y641N/Y641S, respectively. IHMT-EZH2-426 reduces H3K27me3 and EZH2 levels and shows effective anti-proliferative effects in B-cell lymphoma and TNBC cell lines.

Product Properties

• Molecular Weight: 578.70
• CAS Number: [3018914-66-1]
• Formula: C31H35FN4O4S
• Target: Histone Methyltransferase

Application Notes

• Application Notes: Reference compound