ZD06519 (7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin)) is a camptothecin (HY-16560) analogue and a topoisomerase I inhibitor. ZD06519 is an ADC cytotoxin with a strong bystander effect, inhibiting a variety of malignancies such as HER2-positive and FRalpha-overexpressing tumors. ZD06519 inhibits DNA cleavage, relaxation, and reconnection processes, inducing tumor cell death. ZD06519 can be used for ADC synthesis and cancer research[1][2].
Molecular Weight:
497.47
Purity:
98.88
CAS Number:
[2873460-17-2]
Formula:
C25H24FN3O7
Target:
ADC Payload
Application Notes:
MCE Product type: ADC Related
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