PROTAC BRD4 Degrader-21, CAS [[2503036-46-0]] Preis auf Anfrage

Product Overview

• Article Name: PROTAC BRD4 Degrader-21, CAS [[2503036-46-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-156566
• Supplier Catalog Number: HY-156566
• Alternative Catalog Number: MCE-HY-156566-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

PROTAC BRD4 Degrader-21 is a BRD4-targeting PROTAC degrader with an IC50 value of 59 nM. PROTAC BRD4 Degrader-21 induces ubiquitination of BRD4, leading to its degradation via the proteasome. PROTAC BRD4 Degrader-21 binds to recombinant HSP90alpha protein with moderate affinity, having an IC50 of 100-1000 nM. PROTAC BRD4 Degrader-21 induces cancer cell death. PROTAC BRD4 Degrader-21 inhibits tumor growth in xenograft mouse models. PROTAC BRD4 Degrader-21 can be used for the research of acute myeloid leukemia, diffuse large B-cell lymphoma[1].

Product Properties

• Molecular Weight: 925.97
• CAS Number: [2503036-46-0]
• Formula: C47H54Cl2N10O4S
• Target: Epigenetic Reader Domain,HSP,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound