DGKalpha-IN-2 (example 48) is a DGKalpha inhibitor with the IC50 of 0.9 nM, extracted from patent WO2021105115. DGKalpha-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKalpha-IN-2 has the potential for cancer and immunology study.
Molecular Weight:
461.43
Purity:
98.83
CAS Number:
[2648556-92-5]
Formula:
C23H22F3N3O4
Target:
Anaplastic lymphoma kinase (ALK),DGK
Application Notes:
MCE Product type: Reference compound
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