ROCK-IN-9 (Compound T345) is a ROCK inhibitor. ROCK-IN-9 shows cytotoxicity in HepG2 cell, with an IC50 of 40.8 µM. ROCK-IN-9 has good pharmacokinetic properties in mice, and shows high in vivo exposure and oral bioavailability at lower doses[1].
Molecular Weight:
381.40
CAS Number:
[2643334-76-1]
Formula:
C20H20FN5O2
Target:
ROCK
Application Notes:
MCE Product type: Reference compound
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