Nedometinib (NFX-179) is a specific MEK1 inhibitor with an IC50 of 135 nM. Nedometinib inhibits p-ERK, MAPK. Nedometinib exerts anticancer activity against squamous cell carcinoma. Nedometinib can be used for research in dermatosis, neurofibromatosis[1][2].
Molecular Weight:
470.24
Purity:
98.25
CAS Number:
[2252314-46-6]
Formula:
C17H16FIN4O3
Target:
MEK,p38 MAPK,PERK
Application Notes:
MCE Product type: Reference compound
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