NC1 is a selective non-competitive and allosteric lymphoid-specific tyrosine phosphatase (LYP) inhibitor, with a Ki value 4.3 µM. NC1 allosterically regulates LYP/PTPN22 activity by restricting WPD loop movement. NC1 inhibits LYP activity in lymphoid T cells and enhances T-cell receptor signaling. NC1 can be used for the research of autoimmune diseases[1].
Molecular Weight:
546.59
Purity:
98.73
CAS Number:
[445406-82-6]
Formula:
C29H26N2O7S
Target:
ERK,Phosphatase
Application Notes:
MCE Product type: Reference compound
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