BMS-906024 is an orally active and selective gamma-secretase (gamma secretase) inhibitor. BMS-906024 is a potent pan-Notch receptors inhibitor with IC50s of 1.6 nM, 0.7 nM, 3.4 nM, and 2.9 nM for Notch1, -2, -3, and -4 receptors, respectively. BMS-906024 demonstrates broad-spectrum antineoplastic activity[1][2].
Molecular Weight:
556.50
Purity:
99.91
CAS Number:
[1401066-79-2]
Formula:
C26H26F6N4O3
Target:
Notch,gamma-secretase
Application Notes:
MCE Product type: Reference compound
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