GDC-2992, CAS [[2753651-10-2]]

Product Overview

• Article Name: GDC-2992, CAS [[2753651-10-2]]
• Biozol Catalog Number: MCE-HY-156751A
• Supplier Catalog Number: HY-156751A
• Alternative Catalog Number: MCE-HY-156751A-100MG,MCE-HY-156751A-5MG,MCE-HY-156751A-25MG,MCE-HY-156751A-50MG,MCE-HY-156751A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: RO7656594

Product Description

GDC-2992 (Compound 28A) is an orally bioavailable androgen receptor (AR) PROTAC degrader. GDC-2992 degrads AR with a DC50 value of 2.7 nM and inhibits proliferation with an IC50 valude of 9.7 nM in VCaPcells. GDC-2992 can be used for prostatic cancer study. (Structure Note: Pink: target protein ligand (HY-130845), Blue: E3 ligase ligand (HY-W1003189A), Black: linker (HY-169975), E3 ligase ligand +linker (HY-169976A))[1].

Product Properties

• Molecular Weight: 819.39
• Purity: 99.38
• CAS Number: [2753651-10-2]
• Formula: C45H51ClN8O5
• Target: Androgen Receptor,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound