STM3006 is a highly potent, selective, and orally active inhibitor of METTL3 (IC50: 5 nM). STM3006 can reduce the m6A level, promote the formation of dsRNA, trigger a cell-intrinsic interferon response, and enhance the killing effect of T cells on tumors. STM3006 has anti-tumor activity, and its combination with anti-PD-1 immunotherapy yields better results[1][2].
Molecular Weight:
519.44
Purity:
98.71
CAS Number:
[2499664-52-5]
Formula:
C25H27BrN8
Target:
Apoptosis,METTL3
Application Notes:
MCE Product type: Reference compound
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